The effect of comprehensive nursing intervention on treatment adherence in patients with pulmonary tuberculosis
综合护理干预对肺结核患者治疗依从性的影响研究

摘要

目的 探讨综合护理干预对肺结核患者治疗依从性的影响，并分析其对治疗效果及生活质量的改善作用。方法 选取2024年1月-2025年12月某医院收治的肺结核患者60例作为研究对象，采用随机数字表法分为对照组与观察组，各30例。对照组实施常规护理干预，观察组在常规护理基础上实施综合护理干预。比较两组患者治疗依从性评分、痰菌转阴率、健康知识掌握评分以及生活质量评分。结果 观察组治疗依从性评分为（92.46±4.15）分，高于对照组（80.37±5.62）分（t=9.402，P＜0.001）；观察组痰菌转阴率为93.33%，高于对照组73.33%（χ2=4.320，P=0.038）；观察组健康知识掌握评分（90.12±3.98）分明显高于对照组（78.56±5.01）分（t=9.960，P＜0.001）；观察组生活质量评分（85.43±4.27）分明显高于对照组（72.15±6.03）分（t=9.875，P＜0.001）。结论 综合护理干预能够显著提高肺结核患者治疗依从性及健康认知水平，同时提高生活质量并提高痰菌转阴率，具有较高临床推广价值。

Abstract

Objective To explore the impact of comprehensive nursing intervention on treatment adherence in patients with pulmonary tuberculosis and to analyze its effects on treatment outcomes and quality of life.
Methods A total of 60 patients with pulmonary tuberculosis admitted to a hospital between January 2024 and December 2025 were selected as study subjects and randomly divided into a control group and an observation group, each consisting of 30 patients. The control group received routine nursing care, while the observation group received comprehensive nursing intervention based on routine care. The treatment adherence scores, sputum smear conversion rate, health knowledge scores, and quality of life scores of both groups were compared.
Results The treatment adherence score in the observation group was (92.46±4.15) points, significantly higher than that in the control group (80.37±5.62) points (t=9.402, P<0.001). The sputum smear conversion rate in the observation group was 93.33%, higher than that in the control group (73.33%) (χ2=4.320, P=0.038). The health knowledge score in the observation group (90.12±3.98) points was significantly higher than that in the control group (78.56±5.01) points (t=9.960, P<0.001). The quality of life score in the observation group (85.43±4.27) points was also significantly higher than that in the control group (72.15±6.03) points (t=9.875, P<0.001).
Conclusion   Comprehensive nursing intervention significantly improves treatment adherence and health literacy in patients with pulmonary tuberculosis, enhances quality of life, and increases the sputum smear conversion rate, demonstrating high clinical value for widespread application.