Effect of intensive care on the efficacy of noninvasive positive pressure ventilation in patients with COPD complicated by acute respiratory failure
集束化护理对慢阻肺合并急性呼吸衰竭无创正压通气患者的疗效影响

摘要

目的 考察分析集束化护理对慢阻肺（COPD）合并急性呼吸衰竭（ARF）无创正压通气（NPPV）患者的影响。方法 设计一项单盲临床试验，启动期限为2023年9月至2024年8月，纳入本时段多家医院收治的慢阻肺合并呼吸衰竭无创正压通气患者为研究依据，人数共80例，按照1∶1比例进行随机分组，每组（n=40）。实行常规护理的小组命名为参照组，实行集束化护理的小组命名为研究组，最终比对不同干预策略下的疗效作用。比对两组患者肺功能、血气指标、临床疗效、住院时间、并发症发生率差异。结果 研究组各项指标均显优参照组，P＜0.05，值得探讨。结论 集束化护理可有效改善COPD合并ARF患者氧合功能，缩短NPPV治疗时间及住院周期，降低并发症风险，临床疗效显著，值得推广。

Abstract

Objective To examine and analyze the impact of intensive care on patients with chronic obstructive pulmonary disease (COPD) combined with acute respiratory failure (ARF) who are receiving non-invasive positive pressure ventilation (NPPV).
Methods A single-blind clinical trial was designed, with the start period from September 2023 to August 2024. Patients admitted to multiple hospitals during this period were included as the study subjects, totaling 80 cases. They were randomly divided into two groups at a ratio of 1:1, with each group consisting of 40 patients. The group receiving routine care was designated as the control group, while the group receiving intensive care was designated as the treatment group. The effectiveness of different intervention strategies was compared. Pulmonary function, blood gas indicators, clinical outcomes, hospital stay, and complication rates were compared between the two groups.
Results All indicators in the treatment group were significantly better than those in the control group, P<0.05, which is worth further investigation.
Conclusion   Intensive care can effectively improve oxygenation in COPD patients with ARF, shorten the duration of NPPV treatment and hospital stay, reduce the risk of complications, and demonstrate significant clinical efficacy, making it worthy of promotion.