Application of palmtop ultrasound in insulin injection related subcutaneous fat hyperplasia
掌上超声检查在胰岛素注射相关皮下脂肪增生中的应用

摘要

目的 掌上超声检查在胰岛素注射相关皮下脂肪增生中的应用。方法 研究对象为2023年1月份–2023年12月我院65例胰岛素注射相关皮下脂肪增生患者，均实施掌上超声检查及临床检查，统计胰岛素注射相关皮下脂肪增生掌上超声特征，比较联合超声和临床检查对胰岛素注射相关皮下脂肪增生的检出率。结果 掌上超声：超声下显示无血流、无包膜，伴皮肤界限消失的片状高回声者占15.39%（10/65）。无血流、无包膜，伴边界不清晰的均匀一致的团状高回声者占66.15%（43/65）。边界不清晰，在高回声团内包含低回声区占6.15%（4/65）。超声下显示无血流、无包膜，回声欠均匀，边界不清晰占6.15%（4/65）。单纯脂肪层增厚，厚于临近正常脂肪层或对称部位未注射胰岛素脂肪层占6.15%（4/65）。65例患者中，45例（69.23%）临床检查发现胰岛素注射相关皮下脂肪增生，63例（96.92%）超声检查发现胰岛素注射相关皮下脂肪增生。掌上超声检出率比临床检查高，（χ²=14.717，P=0.000）。联合两种方式筛查可进一步提高胰岛素注射相关皮下脂肪增生检出率［100.00%（65/65）］。结论 掌上超声检查在胰岛素注射相关皮下脂肪增生中的应用显著，可推广。

Abstract

Objective To evaluate the application of palmtop ultrasonography in the treatment of subcutaneous fat hyperplasia associated with insulin injection.
Methods The study subjects were 65 patients with insulin injection-related subcutaneous fat hyperplasia in our hospital from January 2023 to December 2023. Palm ultrasound examination and clinical examination were performed for all patients. Palm ultrasound characteristics of insulin injection-related subcutaneous fat hyperplasia were analyzed, and the detection rate of insulin injection-related subcutaneous fat hyperplasia was compared between combined ultrasound and clinical examination.
Results Palmtop ultrasound: 15.39% (10/65) of the patients showed no blood flow, no envelope and disappeared skin boundary. 66.15% (43/65) of the patients had uniform blob hyperechos without blood flow, envelope and boundary ambiguity. The boundary is not clear, and 6.15% (4/65) of high echo clusters contain low echo regions. The ultrasonography showed no blood flow, no envelope, less uniform echo and unclear boundary in 6.15% (4/65). The thickness of the simple fat layer was 6.15% (4/65), which was thicker than the fat layer near the normal fat layer or the fat layer without insulin injection in the symmetric site. Of the 65 patients, 45 (69.23%) found insulin injection-related subcutaneous fat hyperplasia by clinical examination, and 63 (96.92%) found insulin injection-related subcutaneous fat hyperplasia by ultrasound examination. The detection rate of handheld ultrasound was higher than that of clinical examination (χ²=14.717, P=0.000). The combination of the two screening methods could further improve the detection rate of insulin injection-associated subcutaneous fat hyperplasia [100.00% (65/65)].
Conclusion   The application of palmtop ultrasonography in insulin injection related hyperplasia of subcutaneous fat is significant and can be popularized.