Analysis of the efficacy and adverse reactions of midazolam and diazepam in treating febrile convulsions inchildren
咪达唑仑和地西泮治疗小儿高热惊厥的效果及不良反应分析

摘要

目的 分析予以小儿高热惊厥咪达唑仑和地西泮治疗的临床价值。方法 采集本院 2017 年 1 月-2022 年 11 月收治的 100 例小儿高热惊厥患儿为研究对象，将其按照随机数字表形式 1:1 划分为 2 组，对照组咪达唑 仑治疗，观察组地西泮治疗；比较两组疗效、临床指标、患儿依从性、患儿家属满意度及不良反应发生率。结果 观察组疗效高于对照组（P<0.05）。观察组药物起效、惊厥持续、惊厥停止、恢复正常体温、住院时间均短于对 照组（P<0.05）。观察组患儿依从性高于对照组（P<0.05）。观察组患儿家属满意度高于对照组（P<0.05）。观 察组不良反应发生率低于对照组（P<0.05）。结论 予以小儿高热惊厥咪达唑仑和地西泮治疗效果显著，患儿依 从性高，用药不良反应少，患儿家属认可度高，可推广。

Abstract

Objective To analyze the clinical value of midazolam and diazepam in the treatment of febrile convulsions in children.
Methods A total of 100 children with febrile convulsion admitted to our hospital from January 2017 to November 2022 were selected as research objects. They were divided into 2 groups according to a random number table form of 1:1: midazolam in control group and diazepam in observation group; The efficacy, clinical indicators, compliance, family satisfaction and incidence of adverse reactions were compared between the two groups.
Results: The curative effect of observation group was higher than that of control group (P<0.05). Drug onset, duration of convulsion, cessation of convulsion, recovery of normal body temperature and hospital stay in the observation group were shorter than those in the control group (P<0.05). The compliance of observation group was higher than that of control group (P<0.05). The satisfaction of family members in observation group was higher than that in control group (P<0.05). The incidence of adverse reactions in observation group was lower than that in control group (P<0.05).
Conclusion  : Midazolam and diazepam are effective in the treatment of children with febrile convulsion, with high compliance, few adverse reactions, and high recognition degree of children's families, which can be promoted.