摘要
目的 分析消毒供应室中心环氧乙烷灭菌器低温灭菌的应用效果。方法 选择近 3 年（2019 年
1 月-2022 年 2 月）消毒供应室中心的 80 个灭菌包，平均分为两组，一组为传统低温灭菌组（使用 2%强化
戊二醛浸泡法），另一组为环氧乙烷灭菌器低温灭菌组（使用环氧乙烷灭菌器）。结果 两组灭菌效果对比
差异无统计学意义（P>0.05）；环氧乙烷灭菌器低温灭菌组灭菌时间（900±2.5）min，传统低温灭菌组灭菌
时间（600.56±11.46）min。可知，前者灭菌时间更长（P<0.05）；环氧乙烷灭菌器低温灭菌组保存时间
（5.77±1.10）月，传统低温灭菌组（6.07±1.07）月。可知，两组保存时间对比差异无统计学意义（P>0.05）。
结论 环氧乙烷灭菌器灭菌的物品可长期保持无菌，安全有效。与传统低温灭菌相比，环氧乙烷灭菌器对于
不耐高温，高热器械的灭菌方面有较强的优势，大大提升手术安全性，为预防院内感染有重要作用。
关键词： 消毒供应室；环氧乙烷灭菌器；2%强化戊二醛浸泡法；低温；应用；效果
Abstract
Objective To analyze the effect of low temperature sterilization of ethylene oxide sterilizer in the
center of disinfection supply room. Methods 80 sterilization packages in the center of the disinfection and supply
room in recent 3 years (January 2019 February 2022) were selected and divided into two groups on average. One
group was the traditional low-temperature sterilization group (using 2% enhanced glutaraldehyde immersion
method), and the other group was the ethylene oxide sterilizer low-temperature sterilization group (using ethylene
oxide sterilizer). Results There was no significant difference in sterilization effect between the two groups (P>0.05);
Sterilization time of ethylene oxide sterilizer low temperature sterilization group was (900 ± 2.5) min, and that of
traditional low temperature sterilization group was (600.56 ± 11.46) min. It can be seen that the sterilization time of
the former is longer (P<0.05); The storage time of ethylene oxide sterilizer low temperature sterilization group was
（5.77 ± 1.10) months, and that of traditional low temperature sterilization group was (6.07 ± 1.07) months. It can
be seen that there was no statistically significant difference in storage time between the two groups (P>0.05).
Conclusion The products sterilized by ethylene oxide sterilizer can be kept sterile for a long time, safe and
effective. Compared with traditional low-temperature sterilization, ethylene oxide sterilizer has strong advantages
in sterilization of instruments that are not resistant to high temperature and high temperature, greatly improving the
safety of surgery, and playing an important role in preventing hospital infection.
Key words： Disinfection supply room; Ethylene oxide sterilizer; 2% enhanced glutaraldehyde immersionmethod; Low temperature; Application; effect
参考文献 References
[1] 赵艳秋, 邱素红. 环氧乙烷灭菌和低温等离子灭菌对喉镜的灭菌效果[J]. 中华医院感染学杂志, 2022, 32（4）:627-630.
[2] 徐世琴, 张丽香, 薛娟. 环氧乙烷灭菌风险分析与管理[J].实用医药杂志，2020，37（3）：284-286.
[3] 刘亚利. 过氧化氢低温等离子灭菌器在手术器械灭菌质量控制中的应用[J]. 医学理论与实践, 2021, 34（17）:3089-3091.
[4] 黄沛珍, 邢刚, 黄流英,等. 消毒供应室器械使用低温等离子体灭菌器的效果[J]. 中国卫生标准管理, 2022, 13（7）:141-143.
[5] 林黎明. 环氧乙烷灭菌技术在消毒供应室灭菌中的效果观察[J]. 世界最新医学信息文摘, 2020，35（4）：630-632.
[6] 朱胜军, 蔡贤黎, 王萍,等. 两种软式内镜环氧乙烷灭菌包装方法比较[J]. 中国感染控制杂志, 2020, 19（1）:54-57.
[7] 陈慧, 周晓丽, 黄浩,等. 3 种低温灭菌方式下不同包装材料灭菌效果比较[J]. 护理学杂志, 2021, 36（11）:49-51.
[8] 彭伟莲, 程文炜, 易琦峰. 三种灭菌方法对腹腔镜器械的灭菌效果,成本与安全性[J]. 中国感染控制杂志, 2021, 20（8）:711-715.
[9] 李彩艳, 王志超, 刘灵飞,等. 环氧乙烷灭菌和辐照灭菌在医疗器械灭菌中的应用[J]. 中国医疗器械信息, 2020, 26（17）:175-176.