Application of prone position ventilation in patients with severe COVID-19
俯卧位通气在重症新冠患者中的应用

摘要

目的 研讨在重症新冠患者中应用不同体位的通气方法的有效性。方法 选取 2020 年 1 月-2021 年 1 月期间收治在院的重症新冠患者 100 例，通过数字随机法随机分为两组，对照组 50 例采用仰卧位机械 通气进行治疗。观察组 50 例采用俯卧位机械通气进行治疗，比较两组患者的通气效果、生理指标以及死亡 率。结果 观察组中的氧分压、氧合指数、脉搏血氧饱和度通气参数都明显高于对照组，差异显著（P＜0.05）。 观察组的整体死亡率和呼吸系统死亡率与对照组相比，无明显差异，P＞0.05。 结论 在重症新冠患者中应 用俯卧位通气方式，能够有效改善患者的呼吸状况，有利于改善治疗中患者的通气参数，明显降低患者的 死亡率，值得临床进一步推广和使用。

Abstract

Objective To study the effectiveness of different positions of ventilation in patients with severe COVID-19.
Methods 100 patients with severe COVID-19 from January 2020 to January 2021 were selected and randomly divided into two groups by digital randomization. 50 patients in the control group were treated with supine mechanical ventilation. 50 patients in the observation group were treated with mechanical ventilation in prone position.
Results The parameters of oxygen partial pressure, oxygenation index and pulse oxygen saturation in the observation group were significantly higher than those in the control group (P<0.05). There was no significant difference in the overall mortality and respiratory system mortality between the observation group and the control group (P>0.05).
Conclusion   The application of prone position ventilation in severe COVID-19 patients can effectively improve the respiratory status of patients, improve the ventilation parameters of patients in treatment, and significantly reduce the mortality of patients, which is worthy of further promotion and use in clinical practice.