摘要
目的 观察使用胃镜下钛夹止血和奥美拉唑联合治疗溃疡性上消化道出血的效果。方法 随机
将 78 例溃疡性上消化道出血患者分成两组，对照组（38 例）、观察组（40 例）。使用奥美拉唑治疗对照
组，使用胃镜下钛夹止血配合使用奥美拉唑治疗观察组，对比两组止血效果、血流动力学指标、不良反应
发生率。结果 对比两组的止血总有效率，观察组明显高于对照组，组间差异显著（P< 0.05）；治疗第三天
后，比较两组患者的收缩压、心率、舒张压，观察组各项均明显好于对照组，组间差异显著（P<0.05）；比
较两组的不良反应率，没有显著差异（P>0.05）。结论 溃疡性上消化道出血应用胃镜下钛夹止血联合奥美
拉唑，可以起到很好的止血效果，还能使患者的心率、血压得到改善，具有很好的安全性。
关键词： 溃疡性上消化道出血；胃镜；钛夹止血；奥美拉唑
Abstract
Objective To observe the effect of titanium clamp hemostasis combined with omeprazole in the
treatment of ulcerative upper gastrointestinal bleeding under gastroscope. Methods 78 patients with ulcerative
upper gastrointestinal bleeding were randomly divided into two groups: control group (38 cases) and observation
group (40 cases). The control group was treated with omeprazole, and the observation group was treated with
omeprazole with titanium clamp under gastroscope. The hemostatic effect, hemodynamic indexes and incidence of
adverse reactions were compared between the two groups. Results The total hemostatic effective rate of the two
groups was significantly higher in the observation group than in the control group (P< 0.05).After the third day of
treatment, systolic blood pressure, heart rate and diastolic blood pressure of the two groups were compared, and the
observation group was significantly better than the control group, with significant differences between groups
(P<0.05); There was no significant difference in the adverse reaction rate between the two groups (P>0.05).
Conclusion The application of titanium clip hemostasis combined with omeprazole under gastroscope for
ulcerative upper gastrointestinal bleeding can play a good role in hemostasis, but also can improve the heart rate
and blood pressure of patients, with good safety.
Key words： Ulcerative upper gastrointestinal hemorrhage; Gastroscope; Titanium clip hemostasis;omeprazole
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