Clinical application of pathogenic microorganism test in children with bacterial diarrhea
儿童细菌性腹泻的病原微生物检验临床应用

摘要

目的 探讨儿童细菌性腹泻的病原微生物检验临床应用效果。方法 选择我院 2019 年 3 月到 2021 年 3 月 100 例儿童细菌性腹泻患者，本试验对小儿细菌性腹泻进行了病原学检测，并进行了临床应用过程 对各种药物耐药性的分析。结果 100 名儿童通过细菌检测共检测到 81 个细菌菌株，以志贺菌为主，金黄色 葡萄球菌、沙门菌和气单胞菌次之；沙门菌、志贺菌对氨苄西林的耐药性为最高，环丙沙星次之，对阿莫 西林-克拉维酸、头孢吡肟、氨曲南、亚胺培南敏感；气单胞菌属对氨苄青霉素的耐药性为最高，其次是复 方新诺明，环丙沙星，阿莫西林-克拉维酸，头孢吡肟，氨曲南，亚胺培南；金黄色葡萄球菌对青霉素的耐 药性最高，克林霉素次之，对万古霉素和利奈唑胺都有较强的敏感性。结论 通过对小儿细菌性腹泻的检测， 可以明确诊断为细菌感染，通过药物敏感试验，制定相应的治疗方案，提高患儿的临床疗效。其中，志贺 菌是导致小儿细菌性腹泻的重要致病微生物，应将其纳入常规检查，以有效地预防临床上的滥用和误诊， 并对小儿进行及时的诊治，避免延误治疗和引起不良后果。

Abstract

Objective To investigate the clinical application effect of pathogenic microorganism test in children with bacterial diarrhea.
Methods A total of 100 children with bacterial diarrhea in our hospital from March 2019 to March 2021 were selected. In this trial, the etiology of bacterial diarrhea in children was detected, and the drug resistance of various drugs was analyzed during clinical application. .
Results A total of 81 bacterial strains were detected in 100 children, mainly Shigella, followed by Staphylococcus aureus, Salmonella and Aeromonas; the resistance of Salmonella and Shigella to ampicillin was as follows: The highest, followed by ciprofloxacin, sensitive to amoxicillin-clavulanic acid, cefepime, aztreonam, imipenem; Aeromonas was the highest resistance to ampicillin, followed by compound Sulfamethoxazole, ciprofloxacin, amoxicillin-clavulanate, cefepime, aztreonam, imipenem; Staphylococcus aureus had the highest resistance to penicillin, followed by clindamycin, and Both vancomycin and linezolid have strong susceptibility.
Conclusion   Through the detection of bacterial diarrhea in children, the diagnosis of bacterial infection can be confirmed, and the corresponding treatment plan can be formulated through drug sensitivity test to improve the clinical efficacy of children. Among them, Shigella is an important pathogenic microorganism that causes bacterial diarrhea in children, and it should be included in routine examinations to effectively prevent clinical abuse and misdiagnosis, and timely diagnosis and treatment of children to avoid delayed treatment and cause adverse consequences .